all right guys we uh we got a break
coming up
but just but just a few words in closing
okay before we will hear from some
amazing alumni and then head to our
um happy hour on the roof
um today we were lucky enough to hear
some from some of the very best VCS in
the valley thank you guys for that great
conversation
we were able to hear what strategics
look for in startups and we heard some
incredible founder Journeys
and I really really hope that if any of
you were sort of on the fence of
starting a company that at a minimum
you'll reach out to me Serbia
ycommunator.com so we can discuss it
further and I hope that today you're
inspired to take the leap of faith to
build something people need thank you so
much for being here
Mr B okay for this very last session
you're going to get to meet some of the
alumni we have here in the audience so
while uh we have about 20 alumni who are
here today who are going to introduce
themselves briefly on stage they'll have
just 30 seconds or less it's like a mini
demo day almost while we didn't have
time to have every single alumni in the
audience I think Serbia and Jared
mentioned there are about 100 alumni
here today all alumni who are here have
a purple badge so when you were at the
happy hour upstairs uh you know take a
look at everyone's Badges and if they're
purple please feel free to introduce
themselves yourselves to them I'm sure
they're happy to talk about what they're
building uh if you have questions about
their YC Journey about you know uh
starting you know if you need some
advice on starting a company I'm sure
they'd be happy to chat with you so
alumni if I emailed you please make your
way to the right of the stage and uh we
will pass the mic down the line so each
alumni who will come up here will share
their name their two sentence quick you
know YC pitch their description and a
one sentence bio that we'll talk about
you know what they were doing prior to
starting their company all right so
let's have the alumni get started let's
get started with russma
all right hi everyone I'm reshma and I'm
a 10-year member of the YC Community as
part of winter 13 a visiting group
partner and now I'm here repping summer
22 with my company medplum so medplum
makes an open source app building kit
for life sciences and Healthcare as you
folks in the audience might think of us
as it help desk so
um we're really great at integrating
with lots of systems and we are open
source I'll leave you with three parting
thoughts medplum open source we can send
spent help you save many many years of
engineering time contact
[Applause]
[Music]
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hi everyone my name is orianna and I'm
the CEO and co-founder of AOA at AOA we
are developing the first blood test for
the early detection of ovarian cancer so
that we can quickly and accurately catch
the disease at the onset of symptoms
today it takes about nine months in a
very invasive surgery to diagnose
ovarian cancer which leads to about 80
percent of cases being caught when it's
already stage three and four and often
that's too late my background I've been
in the diagnostic space for the last
decade working at two previous Women's
Health startups with both of my
co-founders so either we're good friends
or crazy for doing this again and our
essential Mission has been to bring to
Market Diagnostics with our last two
startups going on to successful exits
thank you
hi everyone I'm Marco Loba CEO of katena
biosciences uh Katana we're doing for
proteins what gingo did for cells we
turn peptides and whole proteins into
modular building blocks that we can
attach to antibodies and cell surfaces
using only native amino acids we've got
two Partnerships going on that we're
starting to develop with major Pharma
and I did my PhD at UC Berkeley in the
labs of Matt Francis and Jennifer doudna
where I discovered the technology behind
katena thank you all so much
hello everyone I'm Patricia bubna and at
our billion we make meat we make lab
grown meat or cell cultured meat the
most delicious meat you've ever eaten
and we start with wagyu beef
and we just recently partnered with a
strategic with a big meat company
because that's what we do and we were
able to slash the cost by 98 with our
high density cell culture platform and
organic technology I did my postdoc at
UC Berkeley and then worked in biopharma
building teams in process development so
we know how to build effective cell
culture companies thank you
thank you
hi everyone my name is Jocelyn I'm the
CTO and co-founder of no text no text
automatically creates visit notes with
billing codes from Doctor patient
conversations our software captures
natural conversation identifies relevant
medical information and then generates a
pre-filled structured note with codes
for Doctor review and sign off before no
text I worked as a medical scribe in
Orthopedics and worked at five different
startups leading Ai and ml teams
[Applause]
hi everyone I'm Catherine Quant at
engage bio we're developing mRNA
Therapeutics to turn tumors into
factories for immunotherapies
our approach results in better efficacy
and less toxicity enabling us to safely
cure solid tumors
before engage I did my PhD at UC
Berkeley studying protein engineering
worked on antibody development at Bayer
and then spent five years at Harpoon
Therapeutics developing by specific
T-cell engagers thanks
[Applause]
hi everyone my name is quid at quadrant
I we are building an online eye exam our
exam enables patients to check their
glasses prescriptions and overall Eye
Health using their phones and laptops
prior to quadrant I I worked as a
cataract surgeon and I trained at Duke
in UCSF thank you
[Applause]
hi my name is Connor and I'm the
co-founder and CEO at pirouette medical
where we are providing convenient Health
Care anywhere we basically do that by
designing a drug delivery system that
allows basically any person without any
training to be able to consistently
perform an injection correctly every
time the best way to demonstrate that is
to just show it to you live
that's literally it uh and we're first
pairing that with epinephrine uh we also
pair with other generics and uh looking
to pair with more pharmaceutical
companies that have drugs that they're
developing or already on the market to
give you a big differentiator prior to
pirouette I received my PhD in medical
engineering and medical physics from MIT
and Harvard Medical School thanks
[Applause]
hi I'm Crystal at insulin we're
developing the next generation of
transplants creating living medicines to
treat diseases like type 1 diabetes the
way it works is cells inside of our
pouch function like little molecular
factories pumping out the molecules
needed to treat diseases like insulin
for type 1 diabetes
we built this technology at UCSF where I
was very lucky to do my PhD and meet my
wonderful co-founder Grace who's back
there you can say hi thanks so much
[Applause]
hi everyone I'm kunj Patel founder of
safe beat we make machine learning
software that powers a hospitalization
at home we target the 2 million new
patients each year diagnosed with atrial
fibrillation who have to go to the
hospital just to start oral pills prior
to founding this company I trained as an
Interventional pain physician at Harvard
and started a private practice from
scratch happy to chat with you all
afterwards
[Applause]
hi I'm uh Daniel kivatinos I'm a
co-founder of a medical records startup
called Dr Chrono Dr Chrono we had
thousands of Physicians and millions of
patients we were doing billions of
dollars in medical claims and uh we just
exited so uh it was a big exit and I'm
here to see everybody here awesome thank
you
[Applause]
these YC pitches never get easier we
haven't exited uh my name is Danny
kranick I'm the CEO and co-founder of
Bristol we analyze the oral microbiome
to help people detect the earliest signs
of oral diseases or cavities come
disease bad breath and we leverage that
data to pair them with personalized care
plans and develop new products cavities
and disease are the most prevalent
diseases on the planet and they're
entirely preventable thanks
oh background in Biochemistry worked at
Illumina for four years
[Applause]
hey everyone I'm Ravi pamnani co-founder
CEO of intact Therapeutics winter 2019.
we are developing novel Therapeutics
with thermal hydrogels to improve drug
delivery to the gut for disorders of the
GI tract and or and certain orphan
diseases we just completed phase one for
our lead candidate in inflammatory bowel
disease and early next year we're
looking to do our series a finally and
also expand our clinical programs I was
originally an engineer then I moved over
to the dark side and last I worked for
Ophthalmology startup and I led
marketing and business development and
we were required by Novartis so I've
seen a little bit of of that side as
well so thanks so much
foreign
hey everyone my name is Akash bakshi I'm
the co-founder and CEO of your choice
Therapeutics and we're developing Next
Generation contraceptives for both men
and women the lead asset is a
non-hormonal pill for men that prevents
men from getting women pregnant it's the
biggest deal in contraception since
condoms came out in the 1860s and it'll
improve the health and well-being of
women because you know let's be honest
men are not great at wearing condoms the
only reversible male contraceptive has
an 18 failure rate so looking forward to
changing the world thanks everyone
thank you
hi I'm Ritu from Genie a genie we are
developing Next Generation therapies for
rare diseases and inflammatory diseases
especially those ones where there's huge
High Health inequities in the country
so we are now a phase two ready phase
two ready
company with 21 plus novel compounds an
AI platform and we are developing
therapies for three different diseases
the first one is ards a horrible disease
with no treatments and the lead cause of
death for influenza as well as for
Corbett
so we're excited about that my
background is I'm a pharmacist by
training and have taken three medicines
from Discovery to FDA approval and as
you would say at demo day this is going
to be the fourth
uh by the way all of this was
accomplished right after demo day so
about three years or so and we spent
about seven million dollars so what
typically takes 10 years and 100 million
so we hope to maintain that and please
show in the journey with Genie
[Applause]
hi everyone I'm Alice co-founder and CSO
of trestle Biotherapeutics Trestle bio
is bioengineering kidneys to treat
kidney failure we're doing this by
combining stem cell biology and 3D
bioprinting to make and grow implantable
kidney tissues to supplement kidney
function
prior to starting Trestle two years ago
I trained as a developmental biologist
at Hopkins and a stem cell biologist at
Harvard University
and prior to this worked at organovo one
of the very first bioprinting efforts to
create 3D human living tissues thank you
[Applause]
hi everyone I'm Alex Federation CEO
co-founder at Talus bio we're developing
first-in-class Therapeutics for
previously undruggable proteins called
transcription factors hundreds of which
are implicated in cancer
we're doing this with next-gen
proteomics
and we're starting with some orphan
pediatric cancers where standard of care
is just chemo radiation and huge unmet
needs so excited to be here thanks for
having us
[Applause]
hey guys so you probably know here pain
 sucks I'm Celine I'm the founder
sucks I'm Celine I'm the founder
of flowley an app for chronic pain
patients what we do is we are an app
that collects your real-time heart rate
and then we convert it into
visualizations in VR that actually teach
you how to control your nervous system
in real time by doing this we can reduce
pain by an average of 46 percent we're
director consumer but as of last month
we're not partnered with one of the
largest insurance companies in the
United States
probably and usually for this crowd I
used to do development at Dreamworks
Animation I'm now principal investigator
on nih-backed clinical trials cheers
[Applause]
hi my name is Catherine cross and I am
the founder of Angel health I founded
Angela health and memory of my younger
brother Andrew who I named the company
after but he had cerebral palsy from an
ear drowning accident and so my parents
were looking into Cord Blood stem cells
to treat him but we couldn't find a cord
blood match so Angel house now helps
pregnant parents keep stem cells from
their umbilical cord and placenta via
cryopreservation so they can use it for
future disease treatment and they don't
have to face the same pain point that my
family did so if you or someone you know
is pregnant we have a YC discount you
can use the code YC baby love but yes
would love to connect with any expecting
parents excited to be here
thank you
hi everyone I'm tuval just standing in
line here I realized the last time I did
this was demo day
and I realized how less stressful this
is so much less stressful
um I was part of YC uh winter batch of
16. I'm the founder of Luke genomics
we're a long read DNA sequencing company
before loop genomics I was the founder
of a synthetic biology company called
sin vaccine before that I did my PhD at
the Weitzman Institute in Israel in
synthetic biology
spent the last six years building Loop
genomics together with a super talented
team of scientists we brought it to a
place where we had a few hundred
customers a few million dollars in
annual recurring revenue and earlier
this year we sold the company to element
biosciences
so I'm happy to connect with all of you
to kind of tell you about the journey
that we had in the past six years
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[Music]
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hi everyone I'm Lucia Huang I'm
co-founder and CEO of osmind at osmind
we offer software and data for mental
health clinicians and researchers we
were YC summer 2020 and Razer series B
earlier this year prior to Osman I've
been on the healthcare side of business
for a number of years on both investing
and previously at a YC bio company
called Verge genomics so thanks
things
hi everyone I'm Tim Boyer with Vino
stents
there are over 5 million dialysis and
bypass surgeries every year they use
veins as replacement arteries but half
of them fail
venosense saves lives with a biles rural
wrap that goes around veins during
surgery
so that they don't fail by training
veins to become like arteries
I did my entire PhD in biomedical
engineering at Vanderbilt University
developing this novel material in
technology we are views it thank you
[Applause]
hello
so pregnancy is hard having a high risk
complication is even harder whether
you're pregnant
we are malama health and we're improving
pregnancy related outcomes starting with
remote monitoring for high risk
perinatal conditions specifically
diabetes and pregnancy which now affects
nearly one in five patients globally
and so far we've attracted nearly 200
patients and seen with these patients a
15 Improvement in percent in range with
our HIPAA compliant app versus the
typical logging methods which are
largely pen and paper today we just
kicked off our first pilot with a large
Hospital 100 Medi-Cal here in NorCal
we're starting our first clinical study
in December with Tufts Medical
and we're looking forward to engaging
with more
um my background is I led clinical
product Innovation at United Healthcare
and Optum
um we are malama Health improving
pregnancy related outcomes thank you
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[Music]
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hi my name is Jose I'm the CEO of shasky
chesky is the one and only company that
has shown that click chemistry can be
used in humans our scientific advice or
Caroline bertozi just received a Nobel
Prize and the press release from the
Nobel Prize committee singled out our
work which was an incredible honor but
something that could not have happened
had YC not invested in an orthopedic
surgery resident
to start a Therapeutics company in
oncology so thank you so much YC we're
now 15 we have raised more than 60
million dollars we have a leading
nationalism phase two and a growing
portfolio of cancer Therapeutics that we
believe are going to revolutionize
Cancer Care thank you so much
[Applause]
thank you Jose and thank you to all the
Alum and the speakers for presenting
today
um one last quick thing I wanted to say
before we head up to happy hour is a big
thank you to YC's event director Lindsay
salvatel who made this happen
all right thank you all and uh we're
excited to meet you upstairs so let's
head over to that PR
oud